Chloroquine: consideration of maximum daily dose (3.5 mg/kg ideal body weight) prevents retinopathy.

نویسندگان

  • F R Ochsendorf
  • U Runne
چکیده

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منابع مشابه

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Chloroquine Retinopathy Ideal body weight Dr. F.R. Ochsendorf, Department of Dermatology, University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt/M. (Germany) In this journal, Lipsker et al. [1] emphasized the efficacy of the combination of chloroquine and quinacrine for the treatment of resistant cutaneous lupus erythematosus. 20% of their patients (3/15), however, developed abnormalities ...

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Incidence of and risk factors for chloroquine and hydroxychloroquine retinopathy in Thai rheumatologic patients

OBJECTIVE To study the incidences of and risk factors for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy in Thai rheumatologic patients. METHODS A retrospective cohort study of 234 rheumatologic patients receiving either CQ or HCQ was conducted. Patients were divided based on whether or not they developed retinopathy as retinopathy-positive or negative groups. Medical records givin...

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Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 Revision).

BACKGROUND The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. PATTERN OF RETINOPATHY Although the locus of toxic damage is parafoveal in many eyes, Asian patients often s...

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(Hydroxy)-chloroquine retinal toxicity: two case reports and safety guidelines.

Retinal toxicity as a result of antimalarial therapy has been reported for many years. Retinopathy may be divided into reversible premaculopathy and irreversible true retinopathy. Risk factors for the development of toxicity are daily dosage related to body weight, total drug dosage and the specific drug used. The daily dosage of chloroquine should not exceed 4 mg/kg lean body weight a day. Exc...

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عنوان ژورنال:
  • Dermatology

دوره 192 4  شماره 

صفحات  -

تاریخ انتشار 1996